Dermatitis Herpetiformis, Celiac, and E.coli ...caused by cross-targeting autoimmunity?

Autoimmune Hypothesis:
Cross-targeting of the immune system by a viral infection marking the inside of a host cell and second infection marking the outside of the host cell causes autoimmune disease where the organ is attacked.  In the case of Celiac disease: Antibodies against e.coli mark the outside of the intestine then an intestinal virus (mono or hepatitis) infection marks the inside of the intestinal cells.

If celiac disease is e.coli then what about Dermatitis Herpetitformis?

Dermatitis Herpetiformis has been correlated with Celiac.  25% of patients with Celiac disease have  HD.
http://celiac.nih.gov/Dermatitis.aspx

D. herpitiformis and  thesmall intestine's bacteria
http://www.ncbi.nlm.nih.gov/pubmed/4210511

E.coli causes small intestine infections
http://www.pathologyoutlines.com/topic/smallbowelEcoli.html

 The e.coli of bladder infections is the same e.coli of skin infections
http://jcm.asm.org/content/47/6/1811

 Bladder Infections and celiac disease in children
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1511510/

Celiac viral infections: hepatitis and adenoviruses (mono)
http://www.sciencedirect.com/science/article/pii/S1568997208002012
http://www.ncbi.nlm.nih.gov/pubmed/25212692
http://www.ncbi.nlm.nih.gov/pubmed/15492610
http://www.ncbi.nlm.nih.gov/pubmed/23982094

Celiac disease found in hepatitis patients
http://www.ncbi.nlm.nih.gov/pubmed/15645466

This page is still under construction...See previous post of mine: Celiac disease as an autoimmune disease where e.coli is connected to gluten through dimorphic switching.

http://www.blogger.com/blogger.g?blogID=2399123431411408462#editor/target=post;postID=5260289305288915498;onPublishedMenu=posts;onClosedMenu=posts;postNum=44;src=postname

Pick's disease, ALS. and microscopic colits

Autoimmune Cross-targeting hypothesis: that 2 infections exist on a target triggering the autoimmunity.  One viral infection marks the inside while another infections marks the outside.

Link to newer review post
http://angelabiggs.blogspot.com/2015/02/over-view-of-brain-autoimmunity.html

Pick's disease and ALS
http://www.ncbi.nlm.nih.gov/pubmed/3322801
http://www.ncbi.nlm.nih.gov/pubmed/21369423
http://www.ncbi.nlm.nih.gov/pubmed/8410013
http://www.ncbi.nlm.nih.gov/pubmed/15068178

Tau with ALS
http://www.neurology.org/content/66/11/1770.abstract

AlS associated protein found in Pick's
http://www.ncbi.nlm.nih.gov/pubmed/23888880

  Can infections of the feet explain the sport association of ALS? Lou Gehrig's disease
 Trichophyton is the most common skin fungus and causes athletes foot.
http://www.ncbi.nlm.nih.gov/pubmed/18578874

 Trichophyton has a wood rot variety.  This could be found in rotting beaver dams....which might explain the ALS clusters around lakes in north America.
http://link.springer.com/article/10.3839%2Fjksabc.2010.026#page-1

I keep wondering if trichophyton is a type of blastomyces....able to cross the blood brain barrier. http://www.ncbi.nlm.nih.gov/pubmed/9703159
or does it need help? obviously people can have ALS and not pick's....does it require strep or a mycobacteria to make the path to the brain?

The intestinal condition of colitis fits with the other fungal infections (Candida and Saccharomyces) causing colitis which is why I am looking for a fungus in ALS.  I am considering hemorrhoids but i have no evidence.

In addition to not being gluten and casein sensitive it must not have the insulin-like factor.
ALS does not have diabetes associated with it. (candida causing microscopic colitis does have type 1 associated with it) This is another way to determine  that the other fungal infections do not cause ALS even if they all look like microscopic colitis.
 Pick's disease involves Tau proteins in the frontotemporal lobe. This is very different from the parkinson's and alzheimer's which may have connections to mycobacterias.

Here is a case where the person had an ALS diagnosis but it wasn't and gluten free solved it. http://www.youtube.com/watch?v=Wliz6Gbg4fE

 Prediction of ALS associated with Hashimoto's thyroid....looking for references now
only personal posts right now http://treato.com/ALS,Hashimoto%27s+Disease/?a=s 

reference als and hashimoto's
http://users.otenet.gr/~dkount/oldpage/8-1.htm

Alzheimer's, parkinson's,Tourettes: How do they overlap?

Alzheimer's I have been viewing as a mitochondrial disease where the nerve gets stuck in growth mode attempting to call mitochondria down the nerves axon.  Mothers of down syndrome children tend to get the early form of Alzheimer's disease. Down syndrome is caused by malfunctioning mitochondria not making enough ATP for dividing the chromosomes correctly.  Without decent ATP levels the mitochondria do not move correctly.

The herpes virus (cold sore) has recently been discovered to cause mitochondrial dysfunction.  The mitochondria do not move where they are suppose to. In 2011 the herpes virus was associated with Alzheimer's disease.  Infecting the neurons in question.
ref
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1796774/
http://www.sciencedaily.com/releases/2011/04/110404122203.htm

So the question is: How did the virus get past the blood brain barrier?  Everyone with cold sore herpes does not have dementia.

Type 2 diabetes has been associated with Alzheimer's disease.  I have postulated that some type 2 diabetes maybe caused by mycobacterias. So perhaps a mycobacteria has broken the blood brain barrier.  Something must be involved in breaking the BBB like strep or t.gondi or a mycobacteria in order for the herpes virus to get into the brain.

Mycobacteria has been debated: http://www.ncbi.nlm.nih.gov/pubmed/10426143

Parkinson's I have associated with mycobacteria and avian flu/flaviviruses possibly causing an autoimmune disease by cross-targeting.  Do Parkinson's patients who develop Alzheimer's have the herpes virus on top? The mycobacteria breaking the BBB allowing both viruses to sneak through a hole for both diseases?

Tourettes I was considering strep followed by a herpes virus. I am reconsidering now.  Do all Tourettes patients develop Alzheimer's ? Strep breaks the blood barrier. This does not make sense because Tourettes patients tend to have enhanced memory skills.  Is alzheimer's only caused by mycobacteria because strep rarely is infecting a patient long enough to allow herpes across and when it does tourettes results instead?

reference of Strep in brains cells and autoimmunity to brain cells in Tourettes or is this Pandas?
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174655/  

reference of herpes and Tourettes
http://www.ncbi.nlm.nih.gov/pubmed/3195682

Must mycobacteria be involve with the herpes virus for Alzheimer's to develop? Tourettes with just strep and herpes infections will only have the autoimmune triggered tics? Or is tourettes so genetic that it only needs strep?  you would think the herpes could cross over and do damage causing Alzheimer's which we do not see.....Tourettes patients tend to have brilliant memories. 

2015 update Tourettes is Genetic while pandas which is tourettes like is autoimmune? http://angelabiggs.blogspot.com/2015/02/over-view-of-brain-autoimmunity.html

Cross-targeting means:
 A first infection marks a target with antibodies on the outside and then a virus marks the inside of a target to the immune system. Hypothesis is that cross-targeting triggers autoimmune disease.

I believe that Alzheimer's is not an autoimmune disease rather a mitochondria dysfunction while parkinson's and Pandas are autoimmune. Maybe?

Could this overlap of infectious culprits explain some of the  overlap we see in some patients with Alzheimer's disease? Could herpes be destroying the mitochondria of some elderly causing some cases of Alzheimer's but the patients can later develop parkinson's because it was a mycobacteria the opened the blood brain barrier?   This means there is no order to Parkinson's or Alzheimer's concerning mycobacteria. one could even get parkinson's first?

Where syn and amyloid plaques appear together mycobacteria exists? With Parkinson's as an autoimmune disease of cross-targeting between a mycobacteria and avian flu/west nile? Can we get syn build up before the autoimmunity? before the parkinson's even if just mycobacteria is there?

Do mothers of down syndrome children have the amyloid plaques? When are the plaques not there? Are they a sign the mitochondria can't move and all Alzheimer patients will have some? But the dementia is really the inability of the mitochondria to move? Obviously their mitochondria has malfunction and herpes did not have to be involved.  Again Alzheimer's would be a mitochondria moving disease.

Can the t.gondi of schizophrenia allow the herpes virus across? Notice a theme of larger infections creating the holes allowing viruses to slip through.

I will research this and post references soon. This page is still under construction. (it is a tad confusing at the moment )

Other things that need to be tied in: the diacetyl link to Alzheimer's disease.  Used as the artificial butter in popcorn and margarine it is also the undesirable butterscotch taste in beer.  The mitochondria of S. cerevisiae make diacetyl during the early stages of fermentation.  My suspicion is that since it comes from a mitochondria....it will interfere in high levels with the function of mitochondria in some kind of negative feedback loop.  Thus the popcorn and alcohol dementia are caused by malfunction mitochondrias not moving?  I really hope this is not true. I can't give up my quality beer or wine....honestly i might choose some mental loss later. Or at least hope that it is really just when overdoses and drinking in moderation is fine....we can hope.  My bet is that extremely high doses are required. That or i have to switch to Red Wine.

diacetyl in popcorn and Alzheimer's
http://www.cbsnews.com/8301-504763_162-57489905-10391704/diacetyl-chemical-in-artificial-butter-popcorn-linked-to-alzheimers-plaque-build-up/

So what might be true...herpes with mycobacteria cause mitochondria dysfunction but alone they may not? Or is it that Tourettes is only a genetic attack on the basal ganglia once strep has broken the barrier regardless of herpes....and herpes only makes things worse later for the Tourettes patient.  And herpes just needs to cross the blood brain barrier (a hole made by any of the infections that can ) in order to cause the mitochondria to malfunction.....maybe?

Schizophrenia which could be an autoimmune attack caused by t.gondi breaking the blood brain barrier has had issues with dementia. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737362
Could these be the patients with the herpes (cold sore) viruses?

update herpes and schizophrenia
http://www.ncbi.nlm.nih.gov/pubmed/15319094

Anyone else have thoughts on this?  Is this possible?