Tentative chemokines hypotheses

Eosinophils hypothesis

Appears that there are 5 types of eosinophils

Complement Eosinophils : C1q,  C3b/C4b, iC3b receptors : Bacteria : granulation

GM-CSF Eosinophils : Low affinity cd32 FcgammaR2 (IgG receptor) : vacuole Bacteria : granulation

il-5 Eosinophils :  cd89 Fc alpha R1(IgA receptor) : Parasites: granulation

il-3 Eosinophils : Fc epsilon R1 (IgE receptor) high affinity:
                              Fc epsilon low affinity receptor

 Viral Eosinophils that contain RNases

il-4 seems involved with antigens outside of the house cell while il-13 seems involved with antigens of the cytosol (visible parasite vs. one that moves into the cytosol of the host cell.



Do the Macrophages clean up the IgE antibodies?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421858/

Do Platelets? They appear to have storage pools if IgE
https://www.sciencedirect.com/science/article/pii/S0091674997702306

Hypothesis: Platelets clean up IgE